Below SSL Cert is required to replace for the SBO Service Layer. Restart the SBO Service Layer after the SSL Cert is replaced.
Please make sure to use the exact same file name.
C:\Program Files\SAP\SAP Business One ServerTools\ServiceLayer\Conf

Stop and start the SBO Service Layer in the correct sequence.
Stop SAP Business One Service Layer Load Balancer
Stop SAP Business One Service Layer Node (500XX)
Start SAP Business One Service Layer Load Balancer
Start SAP Business One Service Layer Node (500XX)